Local anesthetics and their adjuncts

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Local Anesthetics Properties of Local Anesthetics

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Chapter 11 - Local Anesthetics

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Systemic neurotoxicity due to excessive cerebral local anesthetic blood levels is one of the most severe and most frequent adverse outcome of local anesthetic use. Toxic levels are most often produced by unintentional intravenous or intraarterial injection(1,2). Toxicity can also result from the rapid absorption of drug following perineural injection. Peak blood levels are usually obtained acco...

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ژورنال

عنوان ژورنال: Pediatric Anesthesia

سال: 2012

ISSN: 1155-5645

DOI: 10.1111/j.1460-9592.2012.03879.x